Old Mentonians joined the VAFA in 1968 and and in 2018 celebrated their 50th year.
The winning of the 1990 C section flag enabled the club to finish 3rd in B section in 1993. The club's highest finish to date.
2016 saw the Panthers break out of Division 1, by making Grand Final against Old Geelong and enjoy promotion to Premier C. A narrow eight point loss in the Grand Final was the result of a high scoring season in which they won each of the first four games of the season by over 100 points.
Playing out of the Mentone Grammar Keysborough playing fields, the Panthers entered a team in the inaugural VAFA Women's competition and came within two points of a premiership in their first year.
The Club again fields a team in the Under 19 Competition and has recruited a strong list from the School and local clubs and this year celebrates the inaugural U19 side 30 years ago.